The official Lineups for both teams has now been unveiled.
For Southampton, Bazunu is in goal while Armstrong Leeds the attack at St. Mary’s Stadium.
Manchester United remain unchanged, maintaining the same personnel that conquered Liverpool last Monday night.
New Signing, Casemiro, starts from the bench.
Southampton 11: Bazunu; Walker-Peters, Bella Kotchap, Salisu, Djenepo, Lavia, Ward-Prowse (C), Aribo, Elyounoussi, Adams, A. Armstrong.
Subs: McCarthy, Lyanco, Bednarek, Valery, Perraud, O. Romeu, Stewart Armstrong, Mara.
Man UTD 11: De Gea; Martinez, Rafael Varane, D. Dalot, Malacia; Eriksen, McTominay; Bruno Fernandes, Elanga, Sancho; Rashford.
Subs: Heaton, Maguire, Shaw, Wan-Bissaka, Casemiro, Fred, Van De Beek, Garnacho, c. Ronaldo.